PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_3810	Varv-F	"20580652, 25815333, 10075760, 12477048"	"Viola arvensis, Viola tricolor"	Violaceae	"Cyclic Peptide"	"Cytotoxic, Anticancer, Enzymatic-degradation, Antimicrobial"	"participates in a plant defense mechanism.; Shows significant cytotoxic activity; Resist enzymatic degradation in biological fluids."	"Human Myeloma cells RPMI-8226/s (IC50: 5.90 µM),Human Myeloma cells RPMI-8226/Dox40 (IC50: 3.14 µM),Human Myeloma cells RPMI-8226/LR-5 (IC50: 6.31 µM),Human histiocytic lymphoma U-937/GTB (IC50: 7.07 µM),Human histiocytic lymphoma U-937-Vcr (IC50: 7.45 µM),Human renal adenocarcinoma ACHN (IC50: 2.63 µM),Human lymphoblastic leukemia CCRF-CEM (IC50: 7.13 µM),Human lymphoblastic leukemia CCRF-CEM/VM-1 (IC50: 7.15 µM),Human lung carcinoma NCI-H69 (IC50: 7.49 µM),Human lung carcinoma NCI-H69AR (IC50: 7.12 µM),Human glioblastoma U251-MG (IC50: 44.49 µg/ml),Human breast adenocarcinoma MDA-MB-231 (IC50: >10 µg/ml),Human lung carcinoma A549 (IC50: >10 µg/ml),Human prostate cancer DU145 (IC50: >10 µg/ml),Human hepatocarcinoma BEL-7402 (IC50: >10 µg/ml)"	GVPICGETCTLGTCYTAGCSCSWPVCTRN	29	"Experimental evidence at protein level"	2983.43	2981.23	5.96	"HPLC, NMR"	"The structures of this peptide in the crystal, in solution (NMR?ray), and in complex with DPC are nearly identical, indicating structural rigidity and good for engineering (J Biol Chem. 2009 Apr 17;284(16):10672-83). You can rotate, zoom, and view the 3D structure here in the PDB . Updated 2/2014."