PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2213	"Varv peptide E (Cycloviolacin-O12)"	"20580652, 14987049, 10075760, 18618891, 18081258"	"Viola tricolor, Viola arvensis, Viola baoshanensis, Viola yedoensis, Viola tianshanica, Viola abyssinica, Viola philippica"	Violaceae	Cyclotide	"Antiviral, Anticancer, Nematocide, Anti-HIV"	"participates in a plant defense mechanism, Target site: lipid bilayer; shows 50% Hemolysis against Human erythrocytes at 6.96 µM"	"Human glioblastoma U251-MG (IC50: 38.84 µg/ml), Human breast adenocarcinoma MDA-MB-231 (IC50: >10 µg/ml), Human lung carcinoma A549 (IC50: >10 µg/ml), Human prostate cancer DU145 (IC50: >10 µg/ml), Human hepatocarcinoma BEL-7402 (IC50: >10 µg/ml), Human histiocytic lymphoma U-937/GTB (IC50: 4 µM), Human Myeloma cells RPMI-8226/s (IC50: 4 µM)"	GLPICGETCVGGTCNTPGCSCSWPVCTRN	29	"Experimental evidence at protein level"	2916.34	2914.2	5.96	"Amino acid analysis, MS"	"Synthesis Type : Ribosomal, This peptide found in Viola arvensis is also recorded in the UniProtKB entry P83835, The Kalata S showed significant activity in inhibiting development of nematode larvae and motility of adult worms; Shows potential anti-HIV activity; Shown to possess cytotoxic activity in cancer cells."