PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2207	"Kalata B2"	"20564013, 15654741, 28669767, 18618891, 18426225, 18557620, 17534989, 10600388, 11535828"	"Oldenlandia affinis"	Rubiaceae	"Cyclic Peptide"	"Antibacterial, Anticancer, Antifungal, Nematocide, Molluscicidal, Membrane-Binding, Insecticidal, Hemolytic, Antiviral, Antiparasitic"	"The Kalata B2 showed significant activity in inhibiting development of nematode larvae and motility of adult worms; Kalata B2 show potential activity for control of gastrointestinal nematode parasites; Kalata B2 shows molluscicidal activity; Kalata B2 alter membrane permeability leading to the loss of the internal vesicle contents to the external medium; Target site- Lipid Bilayer; 50% Hemolysis against Human erythrocytes at 3.3 ±1.9 µM"	"Escherichia coli (MBC50: 160 µM), Escherichia coli (MBC99: >160 µM), Escherichia coli (MIC: >160 µM), Pseudomonas aeruginosa (MBC50: 40 µM), Pseudomonas aeruginosa (MBC99: 80 µM), Pseudomonas aeruginosa (MIC: 160 µM), Staphylococcus aureus (MBC50: >160 µM), Staphylococcus aureus (MBC99: >160 µM), Staphylococcus aureus (MIC: >160 µM), Candida albicans (MBC50: >160 µM), Candida albicans (MBC99: >160 µM), Candida albicans (MIC: >160 µM), Human histiocytic lymphoma U-937/GTB(IC50: 2.6 µM)"	GLPVCGETCFGGTCNTPGCSCTWPICTRD	29	"Experimental evidence at protein level"	2979.4	2977.2	4.37	"EST, MS, Amino acid analysis, NMR"	"Synthesis Type: Ribosomal; Has insecticidal Activity; Toxic to Golden apple snails, serious pests of rice in South East Asia. Trp can be oxidized into N-formylkynurenine (nfk) or kynurenine (Kyn). The effect of this oxidation on peptide activity is unknown (Plan MR et al. Chembiochem 8: 1001-11). Moderately active against S. aureus (MIC 50 uM) and also reduced bacterial load in vivo (Fensterseifer IC et al., 2014). Also, MIC was reported to be 35 uM performed in 10 mM PBS supplemented with 0.1% TSB in 96-microwell plates (Printing M et al., 2010). You can rotate, zoom, and view the 3D structure here in the PDB . Updated 2/2014; Jan2015; 4/2017."