PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2125	"Cyclotide chassatide C7, Uncyclotide ChaC7"	22467870	"Chassalia chartacea"	Rubiaceae	Cyclotide	"Antibacterial, Anticancer, Cytotoxic, Hemolytic"	"Target site: lipid bilayer; shows 50% Hemolysis against Human erythrocytes at 11.6 µM ; Shown to possess antimicrobial, cytotoxic, and hemolytic activities and the oxidation of two Met residue causes loss of bioactivities, strengthening the importance of the hydrophobic patch for membrane interaction."	"Escherichia coli (MIC: 6.4 µM), Staphylococcus aureus (MIC: >80 µM), Staphylococcus epidermidis (MIC: >80 µM), Human cervical carcinoma HeLa (IC50: 1.2 µM)"	IPCGESCVWIPCITAIAGCSCKNKVCYT	28	"Experimental evidence at protein level"	2963.57	2961.34	7.77	"PcR, MS"	"Synthesis Type : Ribosomal; The compound, however, is also quite toxic (50% hemolysis of human type A blood cells: HL50 11.6 uM). TOXIC TO HeLa cells (IC50 1.2 uM). This is an acyclic peptide. Compared to cyclotides, the C-terminal D/N critical for cyclization is lacking. Surprisingly, this linear form is not only more abundant but also more active than the circular peptides identified in the same plant. APD updated 4/2015."