PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2116	"Cliotide T20"	27007913	"Clitoria ternatea"	Fabaceae	Cyclotide	Antibacterial	"Target site- Lipid Bilayer; Cationic cliotides display potent antibacterial activity against Gram-negative bacteria. It also possess prominent immunostimulating activity. Cationic cliotides are capable of secretion of various cytokines and chemokines in human monocytes at both resting and lipopolysaccharide-stimulated states. Hence also used as potential candidates for novel immunomodulating therapeutics."	"Escherichia coli (MIC: 0.5 µM), Escherichia coli (MIC: 10 µM), Staphylococcus aureus"	GSAIRCGESCLLGKCYTPGCTCDRPICKKN	30	"Experimental evidence at protein level"	3177.75	3175.45	8.66	"NGS, MS"	"Synthesis Type: Ribosomal; Not active up to 100 µM- Staphylococcus aureus; Evidence for bacterial membrane disruption in E. coli. (Nguyen et al., 2016) Treatment with this cyclotide found to cause up-regulation of TNFa and IL-8 in THP-1 cells following LPS stimulation. (Nguyen et al., 2016); APD analysis reveals that the sequence of THE PEPTIDE shows 86.7% similarity to Cliotide T19."