PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2101	Sesquin	15949629	"Vigna unguiculata subsp.sesquipedalis"	Fabaceae	Defensin	"Antibacterial, Antifungal, Antiviral, Anti-HIV, Anticancer"	"Target site: lipid bilayer ; It shows antifungal and antibacterial activity and inhibit the growth of bacteria. It also exerted antiproliferative activity toward breast cancer (MCF-7) cells and leukemia M1 cells. It also exhibit some inhibitory activity toward human immunodeficiency virus-type 1 reverse transcriptase."	"Botrytis cinerea(IC50: 2.5 ±0.01 µM), Botrytis cinerea(IC50: 9.54 ±0.11 µM), Botrytis cinerea(IC50: 8.68 ±0.01 µM), Fusarium oxysporum(IC50: 1.4 ±0.02 µM), Fusarium oxysporum (IC50: 8.1 ±0.07 µM), Fusarium oxysporum(IC50: 7.7 ±0.06 µM ), Mycosphaerella arachidicola(IC50: 0.15 ±0.002 µM), Mycosphaerella arachidicola(IC50: 0.54 ±0.04 µM), Mycosphaerella arachidicola(IC50: 0.84 ±0.02 µM), Proteus vulgaris(IC50: 75 ±6 µM), Mycobacterium phlei (IC50: 87 ±5 µM), Bacillus megaterium(IC50: 105 ±5 µM), Bacillus subtilis(IC50: 98 ±2 µM), Proteus vulgaris, Mycobacterium phlei, Bacillus megaterium, Bacillus subtilis"	KTCENLADTY	10	"Experimental evidence at protein level"	1157.26	1156.51	4.37	"Affi-gel blue gel, Mono S and Superdex 75 columns"	"Synthesis Type : Ribosomal; Exerted antiproliferative activity toward breast cancer (MCF-7) cells and leukemia M1 cells , Sesquin also inhibits HIV-1 reverse transcriptase; Warning: Only the N-terminal sequence of this 7 kDa peptide is available. Active against fungi B. cinerea, F.oxysporum, and M. arachidicola. Inhibit leukemia cells M1 abd breast cancer cells MCF-7. HIV (50 uM inhibit 35%). MOA: see reference title. Updated 12/2017. "
