PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_2071	Ep-AMP1	25821084	"Echinopsis pachanoi"	Cactaceae	Cyclotide	"Antibacterial, Anticancer, Antifungal"	"Target site- Lipid Bilayer, Cysteine-knot peptide shows rapid bactericidal action and liposome leakage that implicates membrane permeabilisation"	"Staphylococcus aureus (MBC: 1.25 µM), Escherichia coli(MBC: 10 µM), Pseudomonas aeruginosa (MBC: 80 µM), Candida albicans (MBC: >160 µM), Human histiocytic lymphoma U-937/GTB(IC50: >100 µM), Staphylococcus aureus, Staphylococcus aureus, Escherichia coli, Escherichia coli, Pseudomonas aeruginosa, Pseudomonas aeruginosa, Candida albicans, Candida albicans"	CVLIGQRCDNDRGPRCCSGQGNCVPLPFLGGVCAV	35	"Experimental evidence at protein level"	3608.22	3605.66	7.78	NMR	"Synthesis Type: Ribosomal; 99% Killing & 50% Killing against Staphylococcus aureus at 0.63 µM & 0.31 µM respectively; 99% Killing & 50% Killing against Escherichia coli at 2.5 µM & 2.5 µM respectively; 99% Killing & 50% Killing against Pseudomonas aeruginosa at 10 µM & 10 µM respectively; 99% Killing & 50% Killing against Candida albicans at >160 µM &160 µM respectively / APD analysis reveals that the sequence of this peptide most resembles (43.6% similarity) Mj-AMP2. Mol Wt: 3590.266; mol formula: C148H246N46O45S6; GRAVY: 0.28. Its activity was more than 500 times higher against bacterial than against eukaryotic cells. Active against S. aureus (MBC 1.25 uM), E. coli (MBC 0.31 uM), and P. aeruginosa (MBC 10 uM, 99% death; 80 uM for 100% death). Ep-AMP1 targets bacterial membranes. You can rotate, zoom, and view the 3D structure here in the PDB . Activity provided by the authors."