PPepDB-ID	"Peptide Name"	PMID	"Plant source"	"Plant Family"	"Peptide Family"	"Peptide function"	"Peptide function description"	"Activity against"	Sequence	"Sequence Length"	Validation	"Avg. Molecular wt(Da)"	"Monoisotopic molecular wt(Da)"	pI	Method	"Additional information"
PPepDB_1924	"Psysol 2"	25894999	"Psychotria solitudinum"	Rubiaceae	Cyclotide	"Enzymatic-degradation, Enzyme-inhibitor"	"Shown to possess proteolytic activity of trypsin or chymotrypsin (IC50=25 µM)"	--NA--	GLPICGESCVGGTCNTPGCTCTWPVCTRN	29	"Experimental evidence at protein level"	2930.37	2928.22	5.96	MS	"APD analysis reveals that the sequence of this peptide most resembles (93.1% similarity) Cycloviolacin O22. Mol. Wt: 2912.4; GRAVY=0.16. It inhibits Human Prolyl Oligopeptidase Activity (IC50 of 25 uM), a target for the cognitive deficits associated with several psychiatric and neurodegenerative diseases, such as schizophrenia and Parkinson's disease. cf. kalata B1 inhibited POP activity with an IC50 of 5.6 uM. "